Efficient dynamic variation graphs
Author(s) -
Jordan M. Eizenga,
Adam M. Novak,
Emily Kobayashi,
Flavia Villani,
Cecilia Cisar,
Simon Heumos,
Glenn Hickey,
Vincenza Colonna,
Benedict Paten,
Erik Garrison
Publication year - 2020
Publication title -
bioinformatics
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btaa640
Subject(s) - mit license , computer science , python (programming language) , implementation , license , computational genomics , call graph , theoretical computer science , graph , genomics , software , programming language , genome , biology , operating system , biochemistry , gene
Pangenomics is a growing field within computational genomics. Many pangenomic analyses use bidirected sequence graphs as their core data model. However, implementing and correctly using this data model can be difficult, and the scale of pangenomic datasets can be challenging to work at. These challenges have impeded progress in this field.
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