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SAINT: self-attention augmented inception-inside-inception network improves protein secondary structure prediction
Author(s) -
Mostofa Rafid Uddin,
Sazan Mahbub,
Mohammad Saifur Rahman,
Md. Shamsuzzoha Bayzid
Publication year - 2020
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btaa531
Subject(s) - computer science , benchmark (surveying) , artificial intelligence , machine learning , artificial neural network , class (philosophy) , data mining , geodesy , geography
Protein structures provide basic insight into how they can interact with other proteins, their functions and biological roles in an organism. Experimental methods (e.g. X-ray crystallography and nuclear magnetic resonance spectroscopy) for predicting the secondary structure (SS) of proteins are very expensive and time consuming. Therefore, developing efficient computational approaches for predicting the SS of protein is of utmost importance. Advances in developing highly accurate SS prediction methods have mostly been focused on 3-class (Q3) structure prediction. However, 8-class (Q8) resolution of SS contains more useful information and is much more challenging than the Q3 prediction.

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