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Chemical–protein interaction extraction via Gaussian probability distribution and external biomedical knowledge
Author(s) -
Cong Sun,
Zhihao Yang,
Leilei Su,
Lei Wang,
Yin Zhang,
Hongfei Lin,
Jian Wang
Publication year - 2020
Publication title -
bioinformatics
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btaa491
Subject(s) - computer science , softmax function , sequence (biology) , gaussian , artificial intelligence , information extraction , source code , relationship extraction , data mining , sentence , knowledge extraction , machine learning , artificial neural network , physics , quantum mechanics , biology , genetics , operating system
The biomedical literature contains a wealth of chemical-protein interactions (CPIs). Automatically extracting CPIs described in biomedical literature is essential for drug discovery, precision medicine, as well as basic biomedical research. Most existing methods focus only on the sentence sequence to identify these CPIs. However, the local structure of sentences and external biomedical knowledge also contain valuable information. Effective use of such information may improve the performance of CPI extraction.

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