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Metaviral SPAdes: assembly of viruses from metagenomic data
Author(s) -
Dmitry Antipov,
Mikhail Raiko,
Alla Lapidus,
Pavel A. Pevzner
Publication year - 2020
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btaa490
Subject(s) - metagenomics , human virome , computational biology , identification (biology) , genome , tree (set theory) , computer science , set (abstract data type) , biology , sequence assembly , genetics , gene , programming language , mathematical analysis , gene expression , botany , mathematics , transcriptome
Although the set of currently known viruses has been steadily expanding, only a tiny fraction of the Earth's virome has been sequenced so far. Shotgun metagenomic sequencing provides an opportunity to reveal novel viruses but faces the computational challenge of identifying viral genomes that are often difficult to detect in metagenomic assemblies.

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