m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human | Zendy

Bowen Song | Zendy; Yujiao Tang | Zendy; Kunqi Chen | Zendy; Zhen Wei | Zendy; Rong Rong | Zendy; Zhi-Liang Lu | Zendy; Jionglong Su | Zendy; João Pedro de Magalhães | Zendy; Daniel J. Rigden | Zendy; Jia Meng | Zendy

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m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human

Author(s) -

Bowen Song,

Yujiao Tang,

Kunqi Chen,

Zhen Wei,

Rong Rong,

Zhi-Liang Lu,

Jionglong Su,

João Pedro de Magalhães,

Daniel J. Rigden,

Jia Meng

Publication year - 2020

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btaa178

Subject(s) - messenger rna , methylation , rna methylation , computational biology , biology , rna , transcriptome , genetics , gene , gene expression , methyltransferase

Recent progress in N7-methylguanosine (m7G) RNA methylation studies has focused on its internal (rather than capped) presence within mRNAs. Tens of thousands of internal mRNA m7G sites have been identified within mammalian transcriptomes, and a single resource to best share, annotate and analyze the massive m7G data generated recently are sorely needed.

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