SCLpred-EMS: subcellular localization prediction of endomembrane system and secretory pathway proteins by Deep N-to-1 Convolutional Neural Networks
Author(s) -
Manaz Kaleel,
Yandan Zheng,
Jialiang Chen,
Xuanming Feng,
Jeremy C. Simpson,
Gianluca Pollastri,
Catherine Mooney
Publication year - 2020
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btaa156
Subject(s) - endomembrane system , subcellular localization , computer science , convolutional neural network , artificial neural network , artificial intelligence , protein subcellular localization prediction , machine learning , biology , microbiology and biotechnology , biochemistry , golgi apparatus , endoplasmic reticulum , cytoplasm , gene
The subcellular location of a protein can provide useful information for protein function prediction and drug design. Experimentally determining the subcellular location of a protein is an expensive and time-consuming task. Therefore, various computer-based tools have been developed, mostly using machine learning algorithms, to predict the subcellular location of proteins.
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