Tally-2.0: upgraded validator of tandem repeat detection in protein sequences | Zendy

Vladimir Perović | Zendy; Jérémy Leclercq | Zendy; Neven Šumonja | Zendy; François Richard | Zendy; Nevena Veljković | Zendy; Andrey V. Kajava | Zendy

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Tally-2.0: upgraded validator of tandem repeat detection in protein sequences

Author(s) -

Vladimir Perović,

Jérémy Leclercq,

Neven Šumonja,

François Richard,

Nevena Veljković,

Andrey V. Kajava

Publication year - 2020

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btaa121

Subject(s) - validator , computer science , mit license , source code , code (set theory) , artificial intelligence , support vector machine , sensitivity (control systems) , annotation , receiver operating characteristic , machine learning , software , pattern recognition (psychology) , data mining , programming language , set (abstract data type) , world wide web , electronic engineering , engineering

Proteins containing tandem repeats (TRs) are abundant, frequently fold in elongated non-globular structures and perform vital functions. A number of computational tools have been developed to detect TRs in protein sequences. A blurred boundary between imperfect TR motifs and non-repetitive sequences gave rise to necessity to validate the detected TRs.

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