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MUM&amp;Co is a single bash script to detect structural variations (SVs) utilizing whole-genome alignment (WGA). Using MUMmer's nucmer alignment, MUM&amp;Co can detect insertions, deletions, tandem duplications, inversions and translocations greater than 50 bp. Its versatility depends upon the WGA and therefore benefits from contiguous de-novo assemblies generated by third generation sequencing technologies. Benchmarked against five WGA SV-calling tools, MUM&amp;Co outperforms all tools on simulated SVs in yeast, plant and human genomes and performs similarly in two real human datasets. Additionally, MUM&amp;Co is particularly unique in its ability to find inversions in both simulated and real datasets. Lastly, MUM&amp;Co's primary output is an intuitive tabulated file containing a list of SVs with only necessary genomic details.

MUM&Co: accurate detection of all SV types through whole-genome alignment