CAFE 5 models variation in evolutionary rates among gene families | Zendy

Fábio K. Mendes | Zendy; Dan Vanderpool | Zendy; Ben Fulton | Zendy; Matthew W. Hahn | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

CAFE 5 models variation in evolutionary rates among gene families

Author(s) -

Fábio K. Mendes,

Dan Vanderpool,

Ben Fulton,

Matthew W. Hahn

Publication year - 2020

Publication title -

bioinformatics

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btaa1022

Subject(s) - variation (astronomy) , scripting language , documentation , phylogenetic tree , computer science , source code , software , tree (set theory) , gene , biology , programming language , genetics , mathematics , mathematical analysis , physics , astrophysics

Genome sequencing projects have revealed frequent gains and losses of genes between species. Previous versions of our software, Computational Analysis of gene Family Evolution (CAFE), have allowed researchers to estimate parameters of gene gain and loss across a phylogenetic tree. However, the underlying model assumed that all gene families had the same rate of evolution, despite evidence suggesting a large amount of variation in rates among families.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research