GpABC: a Julia package for approximate Bayesian computation with Gaussian process emulation
Author(s) -
Evgeny Tankhilevich,
Jonathan Ish-Horowicz,
Tara Hameed,
Elisabeth Roesch,
Istvan T. Kleijn,
Michael P. H. Stumpf,
Fei He
Publication year - 2020
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btaa078
Subject(s) - approximate bayesian computation , emulation , computer science , computation , algorithm , gaussian process , inference , monte carlo method , bayesian probability , bayesian inference , markov chain monte carlo , gaussian , mathematical optimization , theoretical computer science , artificial intelligence , mathematics , statistics , physics , quantum mechanics , economics , economic growth
Approximate Bayesian computation (ABC) is an important framework within which to infer the structure and parameters of a systems biology model. It is especially suitable for biological systems with stochastic and nonlinear dynamics, for which the likelihood functions are intractable. However, the associated computational cost often limits ABC to models that are relatively quick to simulate in practice.
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