Knowledge acquisition, consistency checking and concurrency control for Gene Ontology (GO) | Zendy

Iwei Yeh | Zendy; Peter D. Karp | Zendy; Natalya F. Noy | Zendy; Russ B. Altman | Zendy

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Knowledge acquisition, consistency checking and concurrency control for Gene Ontology (GO)

Author(s) -

Iwei Yeh,

Peter D. Karp,

Natalya F. Noy,

Russ B. Altman

Publication year - 2003

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/19.2.241

Subject(s) - computer science , protégé , consistency (knowledge bases) , programming language , bridging (networking) , uniprot , information retrieval , artificial intelligence , semantic web , computer network , biochemistry , chemistry , gene

A critical element of the computational infrastructure required for functional genomics is a shared language for communicating biological data and knowledge. The Gene Ontology (GO; http://www.geneontology.org) provides a taxonomy of concepts and their attributes for annotating gene products. As GO increases in size, its ongoing construction and maintenance becomes more challenging. In this paper, we assess the applicability of a Knowledge Base Management System (KBMS), Protégé-2000, to the maintenance and development of GO.

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