Reconstruction of DNA sequencing by hybridization | Zendy

Jihong Zhang | Zendy; LingYun Wu | Zendy; Yu Xia | Zendy

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Reconstruction of DNA sequencing by hybridization

Author(s) -

Jihong Zhang,

LingYun Wu,

Yu Xia

Publication year - 2002

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/19.1.14

Subject(s) - dna sequencing , sequencing by hybridization , computational biology , dna , computer science , biology , genetics , dna sequencer

It is widely recognized that the hybridization process is prone to errors and that the future of DNA sequencing by hybridization is predicated on the ability to successfully cope with such errors. However, the occurrence of hybridization errors results in the computational difficulty of the reconstruction of DNA sequencing by hybridization. The reconstruction problem of DNA sequencing by hybridization with errors is a strongly NP-hard problem. So far the problem has not been solved well.

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