UniBLAST: a system to filter, cluster, and display BLASTresults and assign unique gene annotation
Author(s) -
Yan Zhou,
Guyang Matthew Huang,
Liping Wei
Publication year - 2002
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/18.9.1268
Subject(s) - genbank , annotation , gene annotation , computer science , redundancy (engineering) , software , genomics , sequence (biology) , filter (signal processing) , data mining , function (biology) , computational biology , gene , genetics , biology , artificial intelligence , genome , programming language , operating system , computer vision
More and more often, a gene is epitomized by a large number of sequences in GenBank. This high redundancy makes it very difficult to identify a unique best match for a query sequence from its BLAST results. We developed a novel program UniBLAST that filters out uninformative hits, clusters the redundant hits, groups the hits by LocusLink, and graphically displays the results. We also implemented a scoring function in UniBLAST to assign a unique gene name to a query sequence. UniBLAST significantly increases the efficiency of gene annotation.
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