Open AccessA novel approach to local reliability of sequence alignments
Author(s) -
Maximilian Schlosshauer,
Mattias Ohlsson
Publication year - 2002
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/18.6.847
Subject(s) - sequence (biology) , reliability (semiconductor) , computer science , data mining , algorithm , genetics , biology , power (physics) , physics , quantum mechanics
The pairwise alignment of biological sequences obtained from an algorithm will in general contain both correct and incorrect parts. Hence, to allow for a valid interpretation of the alignment, the local trustworthiness of the alignment has to be quantified.
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