BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster | Zendy

Jeffrey D. Grant | Zendy; Roland L. Dunbrack | Zendy; Frank J. Manion | Zendy; Michael F. Ochs | Zendy

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BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster

Author(s) -

Jeffrey D. Grant,

Roland L. Dunbrack,

Frank J. Manion,

Michael F. Ochs

Publication year - 2002

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/18.5.765

Subject(s) - computer science , scalability , license , software , throughput , interface (matter) , database , operating system , bubble , maximum bubble pressure method , wireless

BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through its web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.

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