Exploring the pathway structure of metabolism: decomposition into subnetworks and application to Mycoplasma pneumoniae | Zendy

Stefan Schuster | Zendy; Thomas Pfeiffer | Zendy; F. Moldenhauer | Zendy; Ina Koch | Zendy; Thomas Dandekar | Zendy

Open Access

Exploring the pathway structure of metabolism: decomposition into subnetworks and application to Mycoplasma pneumoniae

Author(s) -

Stefan Schuster,

Thomas Pfeiffer,

F. Moldenhauer,

Ina Koch,

Thomas Dandekar

Publication year - 2002

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/18.2.351

Subject(s) - metabolic network , metabolic pathway , computer science , decomposition , computational biology , petri net , biology , metabolism , programming language , biochemistry , ecology

Reconstructing and analyzing the metabolic map of microorganisms is an important challenge in bioinformatics. Pathway analysis of large metabolic networks meets with the problem of combinatorial explosion of pathways. Therefore, appropriate algorithms for an automated decomposition of these networks into smaller subsystems are needed.

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