Generating samples under a Wright–Fisher neutral model of genetic variation | Zendy

Richard R. Hudson | Zendy

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Generating samples under a Wright–Fisher neutral model of genetic variation

Author(s) -

Richard R. Hudson

Publication year - 2002

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/18.2.337

Subject(s) - wright , statistic , monte carlo method , sampling (signal processing) , statistics , variation (astronomy) , population , sample (material) , computer science , statistical physics , mathematics , demography , physics , sociology , filter (signal processing) , computer vision , thermodynamics , programming language , astrophysics

A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.

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