NIFAS: visual analysis of domain evolution in proteins | Zendy

Christian E. V. Storm | Zendy; Erik L. L. Sonnhammer | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

NIFAS: visual analysis of domain evolution in proteins

Author(s) -

Christian E. V. Storm,

Erik L. L. Sonnhammer

Publication year - 2001

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/17.4.343

Subject(s) - tree (set theory) , phylogenetic tree , domain (mathematical analysis) , computer science , annotation , protein domain , computational biology , sequence alignment , biology , bioinformatics , peptide sequence , genetics , gene , mathematics , combinatorics , mathematical analysis

Multi-domain proteins have evolved by insertions or deletions of distinct protein domains. Tracing the history of a certain domain combination can be important for functional annotation of multi-domain proteins, and for understanding the function of individual domains. In order to analyze the evolutionary history of the domains in modular proteins it is desirable to inspect a phylogenetic tree based on sequence divergence with the modular architecture of the sequences superimposed on the tree.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research