Dynamic simulation of the human red blood cell metabolic network | Zendy

Neema Jamshidi | Zendy; Jeremy S. Edwards | Zendy; Tom Fahland | Zendy; George M. Church | Zendy; Bernhard Ø. Palsson | Zendy

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Dynamic simulation of the human red blood cell metabolic network

Author(s) -

Neema Jamshidi,

Jeremy S. Edwards,

Tom Fahland,

George M. Church,

Bernhard Ø. Palsson

Publication year - 2001

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/17.3.286

Subject(s) - red blood cell , computer science , metabolic network , blood cell , cellular metabolism , biological system , metabolism , computational biology , biology , biochemistry , immunology

We have developed a Mathematica application package to perform dynamic simulations of the red blood cell (RBC) metabolic network. The package relies on, and integrates, many years of mathematical modeling and biochemical work on red blood cell metabolism. The extensive data regarding the red blood cell metabolic network and the previous kinetic analysis of all the individual components makes the human RBC an ideal 'model' system for mathematical metabolic models. The Mathematica package can be used to understand the dynamics and regulatory characteristics of the red blood cell.

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