Open AccessEfficient primer design algorithms
Author(s) -
Thomas Kämpke,
Markus Kieninger,
Michael Mecklenburg
Publication year - 2001
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/17.3.214
Subject(s) - computer science , algorithm , primer (cosmetics) , oligonucleotide , dna , biology , chemistry , organic chemistry , genetics
Primer design involves various parameters such as string-based alignment scores, melting temperature, primer length and GC content. This entails a design approach from multicriteria decision making. Values of some of the criteria are easy to compute while others require intense calculations.
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