Oriloc: prediction of replication boundaries in unannotated bacterial chromosomes | Zendy

A. Carolin Frank | Zendy; Jean R. Lobry | Zendy

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Oriloc: prediction of replication boundaries in unannotated bacterial chromosomes

Author(s) -

A. Carolin Frank,

Jean R. Lobry

Publication year - 2000

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/16.6.560

Subject(s) - replication (statistics) , file transfer protocol , computer science , computational biology , genetics , biology , world wide web , the internet , virology

A program called Oriloc has been developed for the prediction of bacterial replication origins. The method builds on the fact that there are compositional asymmetries between the leading and the lagging strand for replication. The program works with unannotated sequences in fasta format and therefore uses glimmer 2.0 outputs to discriminate between codon positions so as to increase the signal/noise ratio.

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