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GeneRAGE: a robust algorithm for sequence clustering and domain detection
Author(s) -
Anton J. Enright,
Christos Ouzounis
Publication year - 2000
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/16.5.451
Subject(s) - cluster analysis , computer science , false positive paradox , domain (mathematical analysis) , similarity (geometry) , executable , sequence (biology) , smith–waterman algorithm , algorithm , dynamic programming , data mining , pattern recognition (psychology) , sequence alignment , artificial intelligence , mathematics , peptide sequence , image (mathematics) , mathematical analysis , biochemistry , chemistry , biology , gene , genetics , operating system
Efficient, accurate and automatic clustering of large protein sequence datasets, such as complete proteomes, into families, according to sequence similarity. Detection and correction of false positive and negative relationships with subsequent detection and resolution of multi-domain proteins.

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