Self-organization and competition in the immune response to cancer invasion: a phase-orientated computational model of oncogenesis
Author(s) -
Sorinel A. Oprisan,
Aurel Ardelean,
Petre T. Frangopol
Publication year - 2000
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/16.2.96
Subject(s) - carcinogenesis , immune system , competition (biology) , fractal , multifractal system , fractal dimension , cancer , computer science , computational model , dimension (graph theory) , biology , bridge (graph theory) , computational biology , artificial intelligence , immunology , mathematics , genetics , ecology , pure mathematics , mathematical analysis , anatomy
Recent studies indicate that fractal dimensions can uncover aspects of cellular dynamics prior to pathological manifestation. In this respect we are interested in building a computational model of oncogenesis able to generate patterns with the same fractal dimension spectrum as the in vivo tumor.
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