Fast assignment of protein structures to sequences using the Intermediate Sequence Library PDB-ISL | Zendy

Sarah A. Teichmann | Zendy; C. Chothia | Zendy; George M. Church | Zendy; Jong-Eun Park | Zendy

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Fast assignment of protein structures to sequences using the Intermediate Sequence Library PDB-ISL

Author(s) -

Sarah A. Teichmann,

C. Chothia,

George M. Church,

Jong-Eun Park

Publication year - 2000

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/16.2.117

Subject(s) - protein data bank (rcsb pdb) , computer science , sequence (biology) , pairwise comparison , sequence alignment , structural genomics , sequence database , computational biology , bioinformatics , protein structure , biology , genetics , peptide sequence , artificial intelligence , gene , biochemistry

For large-scale structural assignment to sequences, as in computational structural genomics, a fast yet sensitive sequence search procedure is essential. A new approach using intermediate sequences was tested as a shortcut to iterative multiple sequence search methods such as PSI-BLAST.

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