ProtEST: protein multiple sequence alignments from expressed sequence tags | Zendy

James Cuff | Zendy; Ewan Birney | Zendy; Michèle Clamp | Zendy; Geoffrey J. Barton | Zendy

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ProtEST: protein multiple sequence alignments from expressed sequence tags

Author(s) -

James Cuff,

Ewan Birney,

Michèle Clamp,

Geoffrey J. Barton

Publication year - 2000

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/16.2.111

Subject(s) - sequence (biology) , sanger sequencing , sequence alignment , sequence database , protein sequencing , multiple sequence alignment , sequence analysis , web server , computer science , computational biology , biology , data mining , information retrieval , the internet , genetics , peptide sequence , dna sequencing , world wide web , gene

An automatic sequence searching method (ProtEST) is described which constructs multiple protein sequence alignments from protein sequences and translated expressed sequence tags (ESTs). ProtEST is more effective than a simple TBLASTN search of the query against the EST database, as the sequences are automatically clustered, assembled, made non-redundant, checked for sequence errors, translated into protein and then aligned and displayed.

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