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Short interrupted palindromes on the extragenic DNA of Escherichia coli K-12, Haemophilus influenzae and Neisseria meningitidis
Author(s) -
Ana Tereza Ribeiro de Vasconcelos,
Marco A. Grivet Mattoso Maia,
Darcy F. de Almeida
Publication year - 2000
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/16.11.968
Subject(s) - neisseria meningitidis , haemophilus influenzae , microbiology and biotechnology , palindrome , escherichia coli , neisseria , dna , biology , virology , genetics , bacteria , gene , genome , antibiotics
The importance of the various kinds of repetitive nucleotide sequences for the workings of bacterial DNA has been widely recognized. This work is concerned with the distribution of a particular group of repetitive sequences, the short-sequenced interrupted extragenic palindromes, on the genetic maps of Escherichia coli K-12, Haemophilus influenzae Rd and Neisseria meningitidis Z2491 and MC58. A tool has been developed based upon a statistical hypothesis test taking into account the markovian structure of random sequences in order to determine the non-random character of extragenic palindromes.

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