Open AccessK-Estimator: calculation of the number of nucleotide substitutions per site and the confidence intervals
Author(s) -
Josep M. Comeron
Publication year - 1999
Publication title -
computer applications in the biosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1460-2059
pISSN - 0266-7061
DOI - 10.1093/bioinformatics/15.9.763
Subject(s) - estimator , confidence interval , monte carlo method , coding (social sciences) , statistics , divergence (linguistics) , computer science , mathematics , linguistics , philosophy
K-Estimator 4.5 is a Windows program that estimates the number of nucleotide substitutions per site (divergence) when comparing two aligned nucleotide sequences, both protein-coding and non-coding. Confidence intervals of the divergence estimates are obtained by Monte Carlo simulation.
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