Open AccessMathematical simulation and analysis of cellular metabolism and regulation
Author(s) -
Igor Goryanin,
Charlie Hodgman,
E Selkov
Publication year - 1999
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/15.9.749
Subject(s) - workbench , mathematical model , computer science , ordinary differential equation , systems biology , ode , metabolic pathway , mathematics , differential equation , biological system , computational biology , biology , artificial intelligence , metabolism , mathematical analysis , statistics , endocrinology , visualization
A better understanding of the biological phenomena observed in cells requires the creation and analysis of mathematical models of cellular metabolism and physiology. The formulation and study of such models must also be simplified as far as possible to cope with the increasing complexity demanded and exponential accumulation of the metabolic reconstructions computed from sequenced genomes.
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