Open AccessConformational and physicochemical DNA features specific for transcription factor binding sites.
Author(s) -
Julia Ponomarenko,
М. П. Пономаренко,
A S Frolov,
Denis Vorobyev,
G. Christian Overton,
Н. А. Колчанов
Publication year - 1999
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/15.7.654
Subject(s) - dna binding site , dna , java applet , binding site , transcription factor , computational biology , computer science , dna sequencing , database , web site , hmg box , dna binding protein , the internet , biology , genetics , promoter , gene , world wide web , java , gene expression , programming language
A reliable recognition of transcription factor binding sites is essential for analysis of regulatory genomic sequences. The experimental data make evident an important role of DNA conformational features for site functioning. However, Internet-available tools for revealing conformational and physicochemical DNA features significant for the site functioning and subsequent use of these features for site recognition have not been developed up to now.
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