Application of distance geometry to 3D visualization of sequence relationships.
Author(s) -
Mark J. Forster,
Anthony Heath,
Muhammad Afzal
Publication year - 1999
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/15.1.89
Subject(s) - perl , visualization , sequence (biology) , vrml , computer science , sequence alignment , multiple sequence alignment , computer graphics (images) , biology , peptide sequence , programming language , artificial intelligence , gene , genetics , virtual reality
We describe the application of distance geometry methods to the three-dimensional visualization of sequence relationships, with examples for mumps virus SH gene cDNA and prion protein sequences. Sequence-sequence distance measures may be obtained from either a multiple sequence alignment or from sets of pairwise alignments.
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