POLINA: detection and evaluation of single amino acid substitutions in protein superfamilies. | Zendy

S. G. Levin | Zendy; Birgit H. Satir | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

POLINA: detection and evaluation of single amino acid substitutions in protein superfamilies.

Author(s) -

S. G. Levin,

Birgit H. Satir

Publication year - 1998

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/14.4.374

Subject(s) - computer science , source code , code (set theory) , amino acid , position (finance) , identification (biology) , sequence alignment , multiple sequence alignment , protein sequencing , computational biology , algorithm , peptide sequence , data mining , biology , programming language , genetics , finance , gene , economics , botany , set (abstract data type)

An algorithm is described for the quick identification and evaluation of amino acid substitutions in multiple protein sequence alignment. The strategy is based on the calculation of a relative conservation index for an amino acid at each position of the alignment. The algorithm is implemented in the computer program POLINA (Protein Oriented LINear Analysis) which provides a summary of analysis in a format suitable for import into a graphing program.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research