Systematic genomic screening and analysis of mRNA in untranslated regions and mRNA precursors: combining experimental and computational approaches. | Zendy

Thomas Dandekar | Zendy; Katrin Beyer | Zendy; Peer Bork | Zendy; Mary-Rose Kenealy | Zendy; Kostas Pantopoulos | Zendy; Matthias W. Hentze | Zendy; Vera SonntagBuck | Zendy; Gilles Flouriot | Zendy; Frank Gan | Zendy; S Schreiber | Zendy

Open Access

Systematic genomic screening and analysis of mRNA in untranslated regions and mRNA precursors: combining experimental and computational approaches.

Author(s) -

Thomas Dandekar,

Katrin Beyer,

Peer Bork,

Mary-Rose Kenealy,

Kostas Pantopoulos,

Matthias W. Hentze,

Vera SonntagBuck,

Gilles Flouriot,

Frank Gan,

S Schreiber

Publication year - 1998

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/14.3.271

Subject(s) - messenger rna , computational biology , untranslated region , three prime untranslated region , genetics , biology , gene

The untranslated regions (UTRs) of mRNA upstream (5'UTR) and downstream (3'UTR) of the open reading frame, as well as the mRNA precursor, carry important regulatory sequences. To reveal unidentified regulatory signals, we combine information from experiments with computational approaches. Depending on available knowledge, three different strategies are employed.

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