Empirical estimation of the reliability of ribosomal RNA alignments. | Zendy

Elizabeth O’Brien | Zendy; Desmond G. Higgins | Zendy

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Empirical estimation of the reliability of ribosomal RNA alignments.

Author(s) -

Elizabeth O’Brien,

Desmond G. Higgins

Publication year - 1998

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/14.10.830

Subject(s) - computer science , reliability (semiconductor) , sequence (biology) , multiple sequence alignment , ribosomal rna , position (finance) , fidelity , alignment free sequence analysis , data mining , sequence alignment , computational biology , algorithm , artificial intelligence , genetics , biology , gene , physics , telecommunications , power (physics) , finance , quantum mechanics , economics , peptide sequence

The automatic alignment of rRNA sequences can reproduce manual expert alignments with high, but not perfect, fidelity. We examine the use of empirical methods for the identification of regions of an alignment of a new sequence with an existing large alignment which can confidently be predicted to be correctly aligned.

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