Open AccessDisplaying the in formation contents of structural RNA alignments: the structure logos
Author(s) -
Jan Gorodkin,
Laurie J. Heyer,
Søren Brunak,
G.D. Storomo
Publication year - 1997
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/13.6.583
Subject(s) - logos bible software , computer science , nucleic acid structure , rna , computational biology , software , artificial intelligence , biology , genetics , programming language , gene , operating system
We extend the standard 'Sequence Logo' method of Schneider and Stevens (Nucleic Acids Res., 18, 6097-6100, 1990) to incorporate prior frequencies on the bases, allow for gaps in the alignments, and indicate the mutual information of base-paired regions in RNA.
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