Open AccessDISTREE: A tool for estimating genetic distances between aligned DNA sequences
Author(s) -
Johannes Schäfer,
Michael Schöniger
Publication year - 1997
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/13.4.445
Subject(s) - computational biology , computer science , dna , genetics , biology
Substitution rates estimated from aligned DNA data can be used as genetic distances to investigate the phylogenetic relationship of those sequences. For this purpose, a Markov model of nucleotide substitution has to be assumed that describes this process most adequately.
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