Objectively judging the quality of a protein structure from a Ramachandran plot
Author(s) -
Rob Hooft,
Chris Sander,
Gerrit Vriend
Publication year - 1997
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/13.4.425
Subject(s) - ramachandran plot , dihedral angle , plot (graphics) , torsion (gastropod) , computer science , biological system , protein structure , mathematics , chemistry , statistics , biology , zoology , biochemistry , hydrogen bond , organic chemistry , molecule
Statistical methods that compare observed and expected distributions of experimental observables provide powerful tools for the quality control of protein structures. The distribution of backbone dihedral angles ('Ramachandran plot') has often been used for such quality control, but without a firm statistical foundation.
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