A general algorithm to compute multilocus genotype frequencies under various mating systems | Zendy

Frédéric Hospital | Zendy; Christine Dillmann | Zendy; Albrecht E. Melchinger | Zendy

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A general algorithm to compute multilocus genotype frequencies under various mating systems

Author(s) -

Frédéric Hospital,

Christine Dillmann,

Albrecht E. Melchinger

Publication year - 1996

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/12.6.455

Subject(s) - selfing , mating , linkage (software) , mating system , genotype , biology , genetics , algorithm , statistics , mathematics , gene , population , demography , sociology

This paper provides a general method to derive algebraic expressions of genotype frequencies for multiple loci under various mating systems, including random mating, back-crossing, selfing, and full-sib mating. For each mating system, general equations are presented. In the case of three loci, comprehensive tables provide recurrence equations for genotype frequencies under random or self mating, and expected genotype frequencies after two generations of full-sib mating. Our results should prove useful in genetic linkage analysis.

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