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A program for calculating and displaying compatibility matrices as an aid in determining reticulate evolution in molecular sequences
Author(s) -
Ingrid B. Jakobsen,
Simon Easteal
Publication year - 1996
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/12.4.291
Subject(s) - reticulate , compatibility (geochemistry) , reticulate evolution , cluster analysis , computer science , recombination , molecular evolution , computational biology , biology , evolutionary biology , algorithm , genetics , gene , artificial intelligence , phylogenetics , paleontology , materials science , composite material
Reticulate evolution in molecular sequences is caused by recombination or gene conversion, and may interfere with the reconstruction of evolutionary history. This paper presents a program which calculates compatibility matrices for detecting reticulate evolution. In addition to visual inspection of matrices, they can be analysed statistically for clustering. The method is demonstrated using human and chimpanzee gamma-globin sequences.

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