Probing RNA structures and functions by solvent accessibility: an overview from experimental and computational perspectives | Zendy

Md. Solayman | Zendy; Thomas Litfin | Zendy; Jaswinder Singh | Zendy; Kuldip K. Paliwal | Zendy; Yaoqi Zhou | Zendy; Jian Zhan | Zendy

Open Access

Probing RNA structures and functions by solvent accessibility: an overview from experimental and computational perspectives

Author(s) -

Md. Solayman,

Thomas Litfin,

Jaswinder Singh,

Kuldip K. Paliwal,

Yaoqi Zhou,

Jian Zhan

Publication year - 2022

Publication title -

briefings in bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.204

H-Index - 113

eISSN - 1477-4054

pISSN - 1467-5463

DOI - 10.1093/bib/bbac112

Subject(s) - rna , protein tertiary structure , representation (politics) , computer science , function (biology) , solvent , nucleic acid structure , property (philosophy) , feature (linguistics) , computational biology , data science , chemistry , biology , political science , epistemology , biochemistry , microbiology and biotechnology , philosophy , linguistics , politics , law , gene

Characterizing RNA structures and functions have mostly been focused on 2D, secondary and 3D, tertiary structures. Recent advances in experimental and computational techniques for probing or predicting RNA solvent accessibility make this 1D representation of tertiary structures an increasingly attractive feature to explore. Here, we provide a survey of these recent developments, which indicate the emergence of solvent accessibility as a simple 1D property, adding to secondary and tertiary structures for investigating complex structure–function relations of RNAs.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research