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VEGA, the genome browser with a difference
Author(s) -
Jane Loveland
Publication year - 2005
Publication title -
briefings in bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.204
H-Index - 113
eISSN - 1477-4054
pISSN - 1467-5463
DOI - 10.1093/bib/6.2.189
Subject(s) - annotation , genome , pseudogene , gene annotation , genome browser , computational biology , vega , biology , genome project , gene , genomics , computer science , genetics , physics , astronomy
The Vertebrate Genome Annotation (Vega) database is a community resource for browsing manual annotation from a variety of vertebrate genomes of finished sequence (http://vega.sanger.ac.uk). Vega is different from other genome browsers as it has a standardised classification of genes which encompasses pseudogenes and non-coding transcripts. The data is manually curated, which is more accurate at identifying splice variants, pseudogenes poly(A) features, non-coding and complex gene structures and arrangements than current automated methods. The database also contains annotation from regions, not just whole genomes, and displays multiple species annotation (human, mouse, dog and zebrafish) for comparative analysis. Vega encourages community feedback that results in annotation updates and manual annotation of finished vertebrate sequence.

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