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Do it yourself guide to genome assembly
Author(s) -
Bilal Wajid,
Erchin Serpedin
Publication year - 2014
Publication title -
briefings in functional genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.22
H-Index - 67
eISSN - 2041-2647
pISSN - 2041-2649
DOI - 10.1093/bfgp/elu042
Subject(s) - biology , sequence assembly , pipeline (software) , data science , key (lock) , genome , raw data , computational biology , dna sequencing , computer science , genetics , gene , ecology , gene expression , transcriptome , programming language
Bioinformatics skills required for genome sequencing often represent a significant hurdle for many researchers working in computational biology. This humble effort highlights the significance of genome assembly as a research area, focuses on its need to remain accurate, provides details about the characteristics of the raw data, examines some key metrics, emphasizes some tools and draws attention to a generic tutorial with example data that outlines the whole pipeline for next-generation sequencing. The article concludes by pointing out some major future research problems.

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