Genomic approaches in breast cancer research | Zendy

Henry J. Donahue | Zendy; Damian C. Genetos | Zendy

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Genomic approaches in breast cancer research

Author(s) -

Henry J. Donahue,

Damian C. Genetos

Publication year - 2013

Publication title -

briefings in functional genomics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.22

H-Index - 67

eISSN - 2041-2647

pISSN - 2041-2649

DOI - 10.1093/bfgp/elt019

Subject(s) - biology , breast cancer , computational biology , phenotype , genomics , cancer , microarray , gene , bioinformatics , genetics , genome , gene expression

Microarray technologies provide high-throughput analysis of genes that are differentially expressed in humans and other species, and thereby provide a means to measure how biological systems are altered during development or disease states. Within, we review how high-throughput genomic technologies have increased our understanding about the molecular complexity of breast cancer, identified distinct molecular phenotypes and how they can be used to increase the accuracy of predicted clinical outcome.

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