From genotype to phenotype in bovine functional genomics
Author(s) -
Chandra S. Pareek,
Rafał Smoczyński,
Mariusz Pierzchała,
Urszula Czarnik,
Andrzej Tretyn
Publication year - 2011
Publication title -
briefings in functional genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.22
H-Index - 67
eISSN - 2041-2647
pISSN - 2041-2649
DOI - 10.1093/bfgp/elr019
Subject(s) - biology , bovine genome , genomics , genome , phenotype , functional genomics , genotype , genetics , quantitative trait locus , gene annotation , gene , annotation , phenotypic trait , computational biology , whole genome sequencing
In past 5 years, the promise that came with genome sequencing has revolutionized the functional genomics research field at unprecedented manner. It would soon know what all known genes do, particularly genes involved in genetic improvement of animal health and increase food animal production. With the availability of full bovine genomic sequence, yet we still have a lot of daunting tasks on 'genotype-to-phenotype problem' particularly about the phenotypic variations and trying to predict what genes are likely to be involved, and improved integrated interactive database. This article outlined and discussed about the current status of bovine functional genomics, recent development in bovine genome databases particularly in annotation of bovine genome, bovine quantitative trait loci database and its potential impact to unveil the from genotype-to-phenotype problem.
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