The use of covariance models to annotate RNAs in whole genomes
Author(s) -
Paul P. Gardner
Publication year - 2009
Publication title -
briefings in functional genomics and proteomics
Language(s) - English
Resource type - Journals
eISSN - 1477-4062
pISSN - 1473-9550
DOI - 10.1093/bfgp/elp042
Subject(s) - covariance , biology , computational biology , genome , annotation , coding (social sciences) , genetics , computer science , gene , statistics , mathematics
In this review we discuss bioinformatic issues in non-coding RNA analysis, in particular the annotation of genome sequences using covariance models. Some recent innovations for improving the speed and accuracy of covariance models is discussed.
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