Systems biology at the Institute for Systems Biology | Zendy

Leroy Hood | Zendy; L. Rowen | Zendy; David J. Galas | Zendy; John D. Aitchison | Zendy

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Systems biology at the Institute for Systems Biology

Author(s) -

Leroy Hood,

L. Rowen,

David J. Galas,

John D. Aitchison

Publication year - 2008

Publication title -

briefings in functional genomics and proteomics

Language(s) - English

Resource type - Journals

eISSN - 1477-4062

pISSN - 1473-9550

DOI - 10.1093/bfgp/eln027

Subject(s) - hierarchy , systems biology , biology , systems medicine , data science , modelling biological systems , visualization , computer science , discipline , computational biology , management science , engineering ethics , artificial intelligence , engineering , social science , sociology , economics , market economy

Systems biology represents an experimental approach to biology that attempts to study biological systems in a holistic rather than an atomistic manner. Ideally this involves gathering dynamic and global data sets as well as phenotypic data from different levels of the biological information hierarchy, integrating them and modeling them graphically and/or mathematically to generate mechanistic explanations for the emergent systems properties. This requires that the biological frontiers drive the development of new measurement and visualization technologies and the pioneering of new computational and mathematical tools-all of which requires a cross-disciplinary environment composed of biologists, chemists, computer scientists, engineers, mathematicians, physicists, and physicians speaking common discipline languages. The Institute for Systems Biology has aspired to pioneer and seamlessly integrate each of these concepts.

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