Development of quantitative analytical method for volatile thiol compound with LC-ESI-MS as nonvolatile derivative by integrating a thiol-specific derivatization | Zendy

Yusuke Kawano | Zendy; Kengo Suzuki | Zendy; Iwao Ohtsu | Zendy

Open Access

Development of quantitative analytical method for volatile thiol compound with LC-ESI-MS as nonvolatile derivative by integrating a thiol-specific derivatization

Author(s) -

Yusuke Kawano,

Kengo Suzuki,

Iwao Ohtsu

Publication year - 2021

Publication title -

bioscience biotechnology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.509

H-Index - 116

eISSN - 1347-6947

pISSN - 0916-8451

DOI - 10.1093/bbb/zbab129

Subject(s) - derivatization , thiol , chemistry , chromatography , derivative (finance) , electrospray ionization , volatility (finance) , aroma , mass spectrometry , organic chemistry , financial economics , economics , food science

Generally, volatile thiols are hard to be measured with electrospray-ionization-type LC-MS due to the volatility. Therefore, we here evaluated the pretreatment of their S-bimanyl derivatization by monobromobimane to enable the detection as nonvolatile derivative. Consequently, we successfully developed the convenient and efficient method through the quantitative analysis of 2-furanmethanethiol (volatile thiol odorant of coffee aroma) in coffee bean.

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