Neuropsychological And Psychopathological Profile Of Anti-Nmdar Encephalitis: A Possible Pathophysiological Model For Pediatric Neuropsychiatric Disorders | Zendy

Elisa Cainelli | Zendy; Margherita Nosadini | Zendy; Stefano Sartori | Zendy; Agnese Suppiej | Zendy

Open Access

Neuropsychological And Psychopathological Profile Of Anti-Nmdar Encephalitis: A Possible Pathophysiological Model For Pediatric Neuropsychiatric Disorders

Author(s) -

Elisa Cainelli,

Margherita Nosadini,

Stefano Sartori,

Agnese Suppiej

Publication year - 2018

Publication title -

archives of clinical neuropsychology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.909

H-Index - 98

eISSN - 1873-5843

pISSN - 0887-6177

DOI - 10.1093/arclin/acy088

Subject(s) - neuropsychology , apathy , psychopathology , psychology , anti nmda receptor encephalitis , executive functions , impulsivity , psychiatry , clinical psychology , cognition , medicine , nmda receptor , receptor

Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a severe, but treatable, autoimmune disorder, characterized by autoantibodies causing hypofunction of blocking NMDA receptors leading to a unique constellation of cognitive, motor, and psychiatric symptoms. Neuropsychological and psychopathological outcome has not been fully explored, particularly in children. Aim of this study was to investigate pediatric anti-NMDAR encephalitis as a model of impairment of the complex frontal-subcortical circuits who are implicated in several of the childhood neuropsychiatric disorders.

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