Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid β-Associated Cognitive Decline in Older Adults | Zendy

Christa Dang | Zendy; Karra Harrington | Zendy; Yen Ying Lim | Zendy; David Ames | Zendy; Jason Hassenstab | Zendy; Simon M. Laws | Zendy; Nawaf Yassi | Zendy; Martha Hickey | Zendy; Stephanie R. RaineySmith | Zendy; Joanne Robertson | Zendy; Christopher C. Rowe | Zendy; Hamid R. Sohrabi | Zendy; Olivier Salvado | Zendy; Michael Weinborn | Zendy; Victor L. Villemagne | Zendy; Colin L. Masters | Zendy; Paul Maruff | Zendy

Open Access

Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid β-Associated Cognitive Decline in Older Adults

Author(s) -

Christa Dang,

Karra Harrington,

Yen Ying Lim,

David Ames,

Jason Hassenstab,

Simon M. Laws,

Nawaf Yassi,

Martha Hickey,

Stephanie R. RaineySmith,

Joanne Robertson,

Christopher C. Rowe,

Hamid R. Sohrabi,

Olivier Salvado,

Michael Weinborn,

Victor L. Villemagne,

Colin L. Masters,

Paul Maruff

Publication year - 2018

Publication title -

archives of clinical neuropsychology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.909

H-Index - 98

eISSN - 1873-5843

pISSN - 0887-6177

DOI - 10.1093/arclin/acy078

Subject(s) - dementia , cognition , episodic memory , psychology , cognitive decline , alzheimer's disease , hazard ratio , medicine , gerontology , disease , psychiatry , confidence interval

To prospectively examine 8-year risk of clinical disease progression to mild cognitive impairment (MCI)/dementia in older adults ≥60 with superior episodic memory (SuperAgers) compared to those cognitively normal for their age (CNFA). Additionally, to determine the extent to which SuperAgers were resilient to the negative effects of elevated amyloid-beta (Aβ+) on cognition.

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