Co-ordination and divergence of cell-specific transcription and translation of genes in arabidopsis root cells
Author(s) -
Dhivyaa Rajasundaram,
Joachim Selbig,
Staffan Persson,
Sebastian Klie
Publication year - 2014
Publication title -
annals of botany
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.567
H-Index - 176
eISSN - 1095-8290
pISSN - 0305-7364
DOI - 10.1093/aob/mcu151
Subject(s) - biology , arabidopsis , translation (biology) , gene , transcriptome , computational biology , polysome , translational regulation , gene expression , transcription factor , genetics , cell type , arabidopsis thaliana , transcription (linguistics) , regulation of gene expression , cell , messenger rna , microbiology and biotechnology , rna , ribosome , linguistics , philosophy , mutant
A key challenge in biology is to systematically investigate and integrate the different levels of information available at the global and single-cell level. Recent studies have elucidated spatiotemporal expression patterns of root cell types in Arabidopsis thaliana, and genome-wide quantification of polysome-associated mRNA levels, i.e. the translatome, has also been obtained for corresponding cell types. Translational control has been increasingly recognized as an important regulatory step in protein synthesis. The aim of this study was to investigate coupled transcription and translation by use of publicly available root datasets.
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