Microcystin-LR, a protein phosphatase inhibitor, induces alterations in mitotic chromatin and microtubule organization leading to the formation of micronuclei in Vicia faba | Zendy

Dániel Beyer | Zendy; Ildikó Tándor | Zendy; Zoltán Kónya | Zendy; Róbert Bátori | Zendy; Jason Roszik | Zendy; György Vereb | Zendy; Ferenc Erdődi | Zendy; Gábor Vasas | Zendy; Márta MHamvas | Zendy; Károly Jambrovics | Zendy; Csaba Máthé | Zendy

Open Access

Microcystin-LR, a protein phosphatase inhibitor, induces alterations in mitotic chromatin and microtubule organization leading to the formation of micronuclei in Vicia faba

Author(s) -

Dániel Beyer,

Ildikó Tándor,

Zoltán Kónya,

Róbert Bátori,

Jason Roszik,

György Vereb,

Ferenc Erdődi,

Gábor Vasas,

Márta MHamvas,

Károly Jambrovics,

Csaba Máthé

Publication year - 2012

Publication title -

annals of botany

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.567

H-Index - 176

eISSN - 1095-8290

pISSN - 0305-7364

DOI - 10.1093/aob/mcs154

Subject(s) - biology , mitosis , microbiology and biotechnology , chromatin , histone h3 , vicia faba , cell cycle , cytokinesis , metaphase , histone , botany , biochemistry , cell , cell division , dna , chromosome , gene

Microcystin-LR (MCY-LR) is a cyanobacterial toxin, a specific inhibitor of type 1 and 2A protein phosphatases (PP1 and PP2A) with significant impact on aquatic ecosystems. It has the potential to alter regulation of the plant cell cycle. The aim of this study was improved understanding of the mitotic alterations induced by cyanotoxin in Vicia faba, a model organism for plant cell biology studies.

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